Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.53 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.50 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752297 | 0.98 | SIRT2 (0.56) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4952678 | 0.95 | SIRT2 (0.56) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3133609 | 0.93 | HPSE (0.59) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11601557 | 0.93 | HPSE (0.59) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3148419 | 0.93 | HPSE (0.59) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3148356 | 0.93 | HPSE (0.59) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6552751 | 0.91 | HPSE (0.57) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14423593 | 0.91 | ASAH1 (0.53) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13782023 | 0.89 | CYP4Z1 (0.51) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14125304 | 0.88 | SIRT2 (0.50) | SIRT2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | ETH ZURICH (CH) | 2011-07-21 | — | — | US | claimed |
| WO-2010136539-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | COVALX AG (CH) | 2010-12-02 | — | — | WO | claimed |
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | ETH ZURICH (CH) | 2011-07-21 | — | — | US | disclosed |
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | ETH ZURICH (CH) | 2011-07-21 | — | — | US | disclosed |
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | ETH ZURICH (CH) | 2011-07-21 | — | — | US | disclosed |
| WO-2010136539-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | COVALX AG (CH) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010136539-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | COVALX AG (CH) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177617-A1 | CROSS-LINKING REAGENTS FOR MOLECULAR INTERACTIONS ANALYSIS | MTCL3, BICRA, HMGB3 | SIRT2 1266/4885HDAC3 56/4885HDAC4 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.