SCHEMBL2216600

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL996348	0.86	SMPD3 (0.47)	SMPD3ECE1SRCZAP70SYK
	SCHEMBL312885	0.79	MAPT (0.35)	CYP19A1CYP11B1CYP11B2CYP1A1CYP1A2
	SCHEMBL13071433	0.76	SMPD3 (0.46)	SMPD3ECE1SRCZAP70SYK
	SCHEMBL1023279	0.76	PDE4A (0.39)	CYP19A1CYP11B1CYP11B2TSHRMAPK1
	SCHEMBL2214288	0.73	CYP1A1 (0.46)	SMPD3SRCZAP70SYKCYP19A1
	SCHEMBL10194576	0.73	TYR (0.47)	TSHRMAPK1SMN1; SMN2LMNARAB9A
	SCHEMBL6876502	0.72	RXFP1 (0.37)	CYP19A1CYP11B1CYP11B2SMN1; SMN2LMNA
	SCHEMBL4902331	0.72	SMPD3 (0.49)	SMPD3ECE1SRCZAP70SYK
	SCHEMBL315199	0.71	ALDH1A1 (0.37)	CYP19A1CYP11B1CYP11B2CYP1A1CYP1A2
	SCHEMBL16019226	0.70	SMPD3 (0.58)	SMPD3ECE1SRCZAP70SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.