SCHEMBL2214288

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8272307	0.83	SMPD3 (0.47)	CYP1A1CYP1A2CYP1B1SRCZAP70
	SCHEMBL313100	0.78	CYP19A1 (0.40)	CYP1A1CYP1A2CYP1B1CYP19A1KDM4E
	SCHEMBL12732312	0.77	KDM4E (0.58)	KDM4EALDH1A1SMN1; SMN2TACR3RAB9A
	SCHEMBL12055102	0.77	CYP1A2 (0.46)	CYP1A1CYP1A2CYP1B1SRCZAP70
	SCHEMBL1536729	0.77	CYP3A4 (0.51)	KDM4EALDH1A1SMN1; SMN2TACR3TLR8
	SCHEMBL8273118	0.77	CYP1A1 (0.46)	CYP1A1CYP1A2CYP1B1SRCZAP70
	SCHEMBL996348	0.77	SMPD3 (0.47)	CYP1A1CYP1A2CYP1B1SRCZAP70
	SCHEMBL6809626	0.77	ALDH1A1 (0.45)	KDM4EALDH1A1SMN1; SMN2TACR3HPGDS
	SCHEMBL8138975	0.76	KDM4E (0.42)	CYP1A1CYP1A2CYP1B1CYP19A1KDM4E
	SCHEMBL2214881	0.76	POLB (0.47)	CYP19A1KDM4EALDH1A1SMN1; SMN2TACR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.