Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696455 | 0.88 | ESR1 (0.44) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL11204180 | 0.87 | ESR1 (0.47) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL8530735 | 0.84 | PTGS1 (0.50) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL10614146 | 0.84 | PTGS1 (0.50) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL9220172 | 0.84 | PTGS1 (0.50) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL9836121 | 0.84 | PTGS1 (0.50) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL9220178 | 0.84 | PTGS1 (0.50) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL7982997 | 0.83 | ESR1 (0.45) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL7986868 | 0.83 | ESR1 (0.45) | ESR1PTGS1PDE4ACACNA1CABCC2 | |
| SCHEMBL7982994 | 0.83 | ESR1 (0.45) | ESR1PTGS1PDE4ACACNA1CABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10695322-B2 | Inhibitors of bacterial growth | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10695322-B2 | Inhibitors of bacterial growth | DPEP1, PEPD, ANPEP | ESR1 3986/4885PTGS1 742/4885PDE4A 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.