Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22220981 | 0.82 | METAP1 (0.32) | METAP1 | |
| SCHEMBL18656053 | 0.74 | — | — | |
| SCHEMBL19063319 | 0.74 | METAP1 (0.33) | METAP1 | |
| SCHEMBL24722286 | 0.74 | METAP1 (0.33) | METAP1 | |
| SCHEMBL20714587 | 0.70 | METAP1 (0.31) | METAP1 | |
| SCHEMBL1688119 | 0.70 | METAP1 (0.31) | METAP1 | |
| SCHEMBL19502445 | 0.69 | TSHR (0.33) | — | |
| SCHEMBL18030194 | 0.69 | TSHR (0.33) | — | |
| SCHEMBL19485950 | 0.69 | TSHR (0.32) | — | |
| SCHEMBL18480730 | 0.68 | METAP1 (0.30) | METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10695436-B2 | Non-cleavable polymer conjugated with alpha V beta 3 integrin thyroid antagonists | NANOPHARMACEUTICALS, LLC (US) | 2020-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10695436-B2 | Non-cleavable polymer conjugated with alpha V beta 3 integrin thyroid antagonists | THRA, CD44, ITGAV | METAP1 3217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.