Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.43 |
| ▸ | KDM4A | O75164 | 5/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | BCHE | P06276 | 5/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22166501 | 1.00 | KDM4C (0.43) | KDM4CKDM4APHF8KDM2AACACB | |
| SCHEMBL24621812 | 1.00 | KDM4C (0.43) | KDM4CKDM4APHF8KDM2AACACB | |
| SCHEMBL22022221 | 0.87 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2AACACB | |
| SCHEMBL22021685 | 0.84 | EPHX2 (0.41) | KDM4CKDM4APHF8KDM2AACACB | |
| SCHEMBL22021658 | 0.84 | EPHX2 (0.41) | KDM4CKDM4APHF8KDM2AACACB | |
| SCHEMBL22021680 | 0.84 | EPHX2 (0.41) | KDM4CKDM4APHF8KDM2AACACB | |
| SCHEMBL26502029 | 0.83 | CA1 (0.35) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL22564647 | 0.81 | EPHX2 (0.53) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL22166523 | 0.80 | CA1 (0.38) | KDM4CKDM4APHF8KDM2ACHRNB2 | |
| SCHEMBL26479835 | 0.79 | KDM4C (0.44) | KDM4CKDM4APHF8KDM2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696659-B2 | Compounds having estrogen receptor alpha degradation activity and uses thereof | ACCUTAR BIOTECHNOLOGY INC. (US) | 2020-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696659-B2 | Compounds having estrogen receptor alpha degradation activity and uses thereof | ESR2, ESRRG, ESR1 | KDM4C 2564/4885KDM4A 1873/4885PHF8 2612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.