Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 9/20 | 0.38 |
| ▸ | BCHE | P06276 | 8/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729624 | 0.86 | KDM4C (0.39) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL23730160 | 0.86 | KDM4C (0.39) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL22564647 | 0.86 | EPHX2 (0.53) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL23730156 | 0.81 | LMNA (0.38) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL22166501 | 0.79 | KDM4C (0.43) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL22166534 | 0.79 | KDM4C (0.43) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL24621812 | 0.79 | KDM4C (0.43) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL25762207 | 0.78 | CA1 (0.37) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL23730168 | 0.78 | LMNA (0.41) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL636272 | 0.78 | KDM4C (0.46) | KDM4CKDM4APHF8KDM2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |