Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721029 | 0.88 | EPHX2 (0.51) | EPHX2KDM4CPHF8CNR1FFAR4 | |
| SCHEMBL31553201 | 0.88 | EPHX2 (0.51) | EPHX2KDM4CPHF8CNR1FFAR4 | |
| SCHEMBL26479835 | 0.86 | KDM4C (0.44) | EPHX2KDM4CPHF8KDM4AKDM2A | |
| SCHEMBL16675553 | 0.86 | EPHX2 (0.53) | EPHX2KDM4CPHF8KDM4AKDM2A | |
| SCHEMBL22872799 | 0.85 | EPHX2 (0.47) | EPHX2FFAR4FFAR1ALDH1A1CES2 | |
| SCHEMBL21227661 | 0.85 | EPHX2 (0.47) | EPHX2FFAR4FFAR1ALDH1A1CES2 | |
| SCHEMBL25762207 | 0.85 | CA1 (0.37) | EPHX2KDM4CPHF8KDM4AKDM2A | |
| SCHEMBL3627173 | 0.85 | EPHX2 (0.62) | EPHX2KDM4CPHF8CNR1FFAR4 | |
| SCHEMBL7939776 | 0.85 | EPHX2 (0.62) | EPHX2KDM4CPHF8CNR1FFAR4 | |
| SCHEMBL26742538 | 0.84 | EPHX2 (0.48) | EPHX2KDM4CPHF8KDM4AKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020214952-A1 | NOVEL COMPOUNDS HAVING BET, ESTROGEN RECEPTOR, AND ANDROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | ACCUTAR BIOTECHNOLOGY INC. (US) | 2020-10-22 | — | — | WO | disclosed |