Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17968987 | 0.92 | ITGB3 (0.56) | TACR1CTSLCTSBCTSSITGA4 | |
| SCHEMBL16294750 | 0.92 | ITGB3 (0.56) | TACR1CTSLCTSBCTSSITGA4 | |
| SCHEMBL16294752 | 0.92 | ITGB3 (0.56) | TACR1CTSLCTSBCTSSITGA4 | |
| SCHEMBL15019911 | 0.88 | ITGB3 (0.48) | ALDH1A1ALOX15TACR1CTSLCTSB | |
| SCHEMBL15019914 | 0.88 | ITGB3 (0.48) | ALDH1A1ALOX15TACR1CTSLCTSB | |
| SCHEMBL16295347 | 0.87 | CAPN1 (0.55) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL15019763 | 0.86 | ITGB3 (0.49) | ALDH1A1ALOX15TACR1CTSLCTSB | |
| SCHEMBL17532279 | 0.86 | TACR1 (0.51) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL22167247 | 0.86 | TACR1 (0.51) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL14338213 | 0.85 | ALDH1A1 (0.67) | ALDH1A1ALOX15TACR1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |