Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17539188 | 1.00 | F2 (0.33) | F2ST14ITGB3ITGA2BPRCP | |
| SCHEMBL22167172 | 0.96 | F2 (0.33) | F2PRCPPLGPLAUF10 | |
| SCHEMBL17459540 | 0.96 | F2 (0.33) | F2PRCPPLGPLAUF10 | |
| SCHEMBL17459547 | 0.96 | F2 (0.32) | F2ITGB3ITGA2BP2RY12 | |
| SCHEMBL22167416 | 0.96 | F2 (0.32) | F2ITGB3ITGA2BP2RY12 | |
| SCHEMBL17492937 | 0.95 | F2 (0.34) | F2ITGB3ITGA2BPRCPPLG | |
| SCHEMBL17492938 | 0.95 | F2 (0.34) | F2ITGB3ITGA2BPRCPPLG | |
| SCHEMBL22167188 | 0.92 | F2 (0.31) | F2 | |
| SCHEMBL17459563 | 0.92 | F2 (0.31) | F2 | |
| SCHEMBL17492907 | 0.92 | F2 (0.31) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |