Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459547 | 1.00 | F2 (0.32) | F2ITGB3ITGA2BPYGLP2RY12 | |
| SCHEMBL22167188 | 0.96 | F2 (0.31) | F2PYGL | |
| SCHEMBL17492907 | 0.96 | F2 (0.31) | F2PYGL | |
| SCHEMBL17459563 | 0.96 | F2 (0.31) | F2PYGL | |
| SCHEMBL22167333 | 0.96 | F2 (0.33) | F2ITGB3ITGA2BP2RY12 | |
| SCHEMBL17539188 | 0.96 | F2 (0.33) | F2ITGB3ITGA2BP2RY12 | |
| SCHEMBL21878967 | 0.94 | F2 (0.33) | F2PYGL | |
| SCHEMBL17492914 | 0.94 | F2 (0.33) | F2PYGL | |
| SCHEMBL20026745 | 0.94 | F2 (0.33) | F2PYGL | |
| SCHEMBL17492915 | 0.94 | F2 (0.33) | F2PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |