Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532303 | 1.00 | PYGL (0.32) | PYGLPRCPITGB1ITGA4ITGB7 | |
| SCHEMBL17468603 | 0.94 | PYGL (0.33) | PYGLPRCPCDK9NPC1 | |
| SCHEMBL17532306 | 0.90 | PYGL (0.33) | PYGLPRCPNPC1 | |
| SCHEMBL17532336 | 0.89 | PRCP (0.32) | PYGLPRCPITGB1ITGA4ITGB7 | |
| SCHEMBL20026803 | 0.89 | PRCP (0.32) | PYGLPRCPITGB1ITGA4ITGB7 | |
| SCHEMBL17532281 | 0.89 | PYGL (0.35) | PYGLPRCPCDK9NPC1 | |
| SCHEMBL17532305 | 0.89 | PYGL (0.32) | PYGLPRCP | |
| SCHEMBL17532309 | 0.88 | F2 (0.32) | PYGLPRCPITGB1 | |
| SCHEMBL22167241 | 0.88 | PYGL (0.32) | PYGLPRCP | |
| SCHEMBL17492920 | 0.88 | PYGL (0.32) | PYGLPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |