Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532299 | 1.00 | PYGL (0.31) | PYGLENPP2PIK3CDPRCPMC4R | |
| SCHEMBL17492910 | 0.93 | S1PR4 (0.36) | PYGL | |
| SCHEMBL19181503 | 0.93 | S1PR4 (0.36) | PYGL | |
| SCHEMBL17492911 | 0.93 | S1PR4 (0.36) | PYGL | |
| SCHEMBL22167489 | 0.93 | S1PR4 (0.36) | PYGL | |
| SCHEMBL22167387 | 0.92 | PYGL (0.32) | PYGLPRCPMC4R | |
| SCHEMBL17532287 | 0.92 | PYGL (0.32) | PYGLPRCPMC4R | |
| SCHEMBL17532290 | 0.91 | PYGL (0.33) | PYGLMC4RITGB3ITGA2B | |
| SCHEMBL22167480 | 0.91 | S1PR1 (0.36) | PYGLENPP2 | |
| SCHEMBL17532291 | 0.91 | S1PR1 (0.36) | PYGLENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |