Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 5/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.35 |
| ▸ | MME | P08473 | 5/20 | 0.35 |
| ▸ | ACE | P12821 | 5/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.35 |
| ▸ | CPA1 | P15085 | 4/20 | 0.35 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.34 |
| ▸ | TPH1 | P17752 | 1/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.33 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.33 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532369 | 1.00 | ITGA4 (0.35) | ITGA4ITGB7ITGB1MMEACE | |
| SCHEMBL17492913 | 0.93 | KIFC1 (0.33) | ITGA4ITGB7ITGB1MMEACE | |
| SCHEMBL17492912 | 0.93 | KIFC1 (0.33) | ITGA4ITGB7ITGB1MMEACE | |
| SCHEMBL17532371 | 0.93 | KIFC1 (0.33) | ITGA4ITGB7ITGB1MMEACE | |
| SCHEMBL22167414 | 0.93 | KIFC1 (0.33) | ITGA4ITGB7ITGB1MMEACE | |
| SCHEMBL17468487 | 0.92 | KIFC1 (0.34) | ITGA4ITGB7ITGB1MMEACE | |
| SCHEMBL17532368 | 0.92 | KIFC1 (0.34) | ITGA4ITGB7ITGB1MMEACE | |
| SCHEMBL19695867 | 0.92 | KIFC1 (0.34) | ITGA4ITGB7ITGB1MMEACE | |
| SCHEMBL22167479 | 0.91 | KIFC1 (0.35) | ITGA4ITGB7ITGB1MMEACE | |
| SCHEMBL17539189 | 0.91 | KIFC1 (0.35) | ITGA4ITGB7ITGB1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |