SCHEMBL22167657

SCHEMBL22167657

Cn1ccc([SH](C)(N)=O)c1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
INMT O95050 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3078481 0.66
SCHEMBL14648466 0.62 ACHE (0.42) CA12CA1CA2CA9
SCHEMBL1662883 0.61
SCHEMBL17233960 0.61
Iodide SCHEMBL27502072 0.59
Hydrochloric Acid SCHEMBL1353327 0.59
SCHEMBL22167672 0.58
SCHEMBL7468780 0.58 CA2 (0.57) CA12CA1CA2CA9
SCHEMBL5062781 0.58
SCHEMBL1905622 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020135771-A1 HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2020-07-02 WO disclosed