⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716246 | 0.84 | — | — | |
| SCHEMBL285899 | 0.80 | — | — | |
| SCHEMBL10614207 | 0.80 | — | — | |
| Azetidine SCHEMBL6112491 | 0.80 | ALDH1A1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL2306666 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL518222 | 0.77 | — | — | |
| SCHEMBL13504570 | 0.77 | — | — | |
| SCHEMBL11057613 | 0.76 | — | — | |
| SCHEMBL14523169 | 0.73 | — | — | |
| SCHEMBL20309204 | 0.73 | CHKA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240140915-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-05-02 | — | — | US | claimed |
| WO-2024092185-A1 | ACYL SULFONAMIDE COMPOUNDS AS INHIBITORS OF POLYOMAVIRUS | VIA NOVA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | claimed |
| US-20240124489-A1 | SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2024-04-18 | — | — | US | claimed |
| US-20240101553-A1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2024-03-28 | — | — | US | claimed |
| US-20240067612-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-02-29 | — | — | US | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| WO-2024010782-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | claimed |
| US-11655243-B2 | Pyridine and pyrazine derivatives as preferential cannabinoid 2 agonists | HOFFMANN-LA ROCHE INC. (US) | 2023-05-23 | — | — | US | claimed |
| US-20220289739-A1 | SUBSTITUTED BENZIMIDAZOLONE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2022-09-15 | — | — | US | claimed |
| CN-114126713-A | Substituted benzimidazolone compounds | 百时美施贵宝公司 | 2022-03-01 | — | — | CN | claimed |
| CN-104837818-A | Pyridine-2-amides useful as CB2 agonists | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | claimed |
| CN-104768950-A | Pyrazine derivatives | HOFFMANN LA ROCHE | 2015-07-08 | — | — | CN | claimed |
| CN-104364249-A | Triazolo compounds as pde10 inhibitors | BOSCH GMBH ROBERT | 2015-02-18 | — | — | CN | claimed |
| CN-104271566-A | Substituted dipyridylamines and uses thereof | HOFFMANN LA ROCHE | 2015-01-07 | — | — | CN | claimed |
| US-20140371464-A1 | PROCESS FOR THE PREPARATION OF CHIRAL ISOXAZOLINE AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS SERVICES LLC | 2014-12-18 | — | — | US | claimed |
| EP-2809667-A1 | PROCESS FOR THE PREPARATION OF CHIRAL ISOXAZOLINE AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2014-12-10 | — | — | EP | claimed |
| CN-104169276-A | Process for the preparation of chiral isoxazoline azetidine derivatives as antiparasitic agents | ZOETIS LLC | 2014-11-26 | — | — | CN | claimed |
| CN-103974948-A | Substituted benzyl indazoles as BUB1 kinase inhibitors in the treatment of hyperproliferative diseases | Bayer Pharma AG | 2014-08-06 | — | — | CN | claimed |
| CN-102459162-B | Novel cyclopentane derivatives | HOFFMANN LA ROCHE | 2014-01-08 | — | — | CN | claimed |
| WO-2013116236-A1 | PROCESS FOR THE PREPARATION OF CHIRAL ISOXAZOLINE AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS LLC (US) | 2013-08-08 | — | — | WO | claimed |