⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10614207 | 0.95 | — | — | |
| SCHEMBL23598636 | 0.95 | — | — | |
| SCHEMBL285899 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL1442403 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL518222 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL2306666 | 0.91 | — | — | |
| SCHEMBL13504570 | 0.91 | — | — | |
| SCHEMBL221682 | 0.84 | — | — | |
| SCHEMBL18245095 | 0.79 | CA1 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL3552982 | 0.72 | MLYCD (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111247152-B | Cyclic iminopyrimidine derivatives as kinase inhibitors | 璧辰医药技术股份有限公司 | 2024-07-16 | — | — | CN | claimed |
| US-20240218022-A1 | ANTI-VISTA MACROCYCLIC PEPTIDES AND COMPOSITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-04 | — | — | US | claimed |
| EP-3468953-B1 | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-05-22 | — | — | EP | claimed |
| WO-2024102884-A1 | SUBSTITUTED QUINOLONE COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-16 | — | — | WO | claimed |
| US-20240101553-A1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2024-03-28 | — | — | US | claimed |
| EP-4263541-A1 | NEW ARYL-PYRIDO-PYRIMIDIN-ONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-10-25 | — | — | EP | claimed |
| EP-4263518-A1 | NEW QUINAZOLINONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-10-25 | — | — | EP | claimed |
| US-20230331682-A1 | NEW QUINAZOLINONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-10-19 | — | — | US | claimed |
| US-20230322776-A1 | NEW ARYL-PYRIDO-PYRIMIDIN-ONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-10-12 | — | — | US | claimed |
| CN-219783877-U | Chiral separation column for fluorinated pyrrolidine | 南京德克瑞医药化工有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-104039791-A | [1,2,3] triazolo [4,5-D ] pyrimidine derivatives as cannabinoid receptor 2 agonists | HOFFMANN LA ROCHE | 2014-09-10 | — | — | CN | claimed |
| CN-103987698-A | 2-Phenylaminopyrimidine derivatives as kinase LRRK2 modulators for the treatment of Parkinson's disease | HOFFMANN LA ROCHE | 2014-08-13 | — | — | CN | claimed |
| CN-102459162-B | Novel cyclopentane derivatives | HOFFMANN LA ROCHE | 2014-01-08 | — | — | CN | claimed |
| US-8455479-B2 | Heterocyclic compounds | PANACEA BIOTEC LIMITED (IN) | 2013-06-04 | — | — | US | claimed |
| US-8354405-B2 | 6-cycloamino-3-(pyrid-4-yl)imidazo[1,2-b]pyridazine derivatives, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2013-01-15 | — | — | US | claimed |
| US-20100174096-A1 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives | IM&T RESEARCH, INC. (US) | 2010-07-08 | — | — | US | claimed |
| CN-1980662-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-06-13 | — | — | CN | claimed |
| US-20020082258-A1 | Novel bicyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION & REDDY- CHEMINOR, INC. | 2002-06-27 | — | — | US | claimed |
| US-20010051619-A1 | Novel bicyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION AND REDDY-CHEMINOR, INC. | 2001-12-13 | — | — | US | claimed |
| US-6265401-B1 | ANTIDIABETIC AGENTS | REDDY-CHEMINOR, INC. | 2001-07-24 | — | — | US | claimed |