SCHEMBL221689

SCHEMBL221689

c1ccc2c(c1)C1CCC2C1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRNB4 P30926 1/20 0.59
CHRNA3 P32297 1/20 0.59
IDO1 P14902 2/20 0.38
HTR2C P28335 2/20 0.38
PDPK1 O15530 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
AKR1C3 P42330 1/20 0.37
AKR1C1 Q04828 1/20 0.37
KDM1A O60341 2/20 0.36
KDM1B Q8NB78 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30166929 1.00 CHRNB4 (0.59) CHRNB4CHRNA3IDO1HTR2CPDPK1
SCHEMBL23797352 1.00 CHRNB4 (0.59) CHRNB4CHRNA3IDO1HTR2CPDPK1
SCHEMBL11704162 0.88 CHRNB4 (0.54) CHRNB4CHRNA3HTR2CPDPK1
SCHEMBL2913571 0.88 CHRNB4 (0.54) CHRNB4CHRNA3HTR2CPDPK1CHRNB2
SCHEMBL3425103 0.87 CHRNB4 (0.50) CHRNB4CHRNA3IDO1HTR2CPDPK1
SCHEMBL6940509 0.87 CHRNB4 (0.50) CHRNB4CHRNA3IDO1HTR2CPDPK1
SCHEMBL11704954 0.86 CHRNB4 (0.52) CHRNB4CHRNA3HTR2C
SCHEMBL11701290 0.86 CHRNB4 (0.52) CHRNB4CHRNA3HTR2C
SCHEMBL16099720 0.85 CHRNB4 (0.46) CHRNB4CHRNA3IDO1PDPK1CHRNB2
Benzoic Acid SCHEMBL11807312 0.80 TSHR (0.56) CHRNB4CHRNA3AKR1C3AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178203-B Polyimide containing amide bond and benzonorbornane structure and preparation method thereof 南昌大学 2025-02-14 CN claimed
CN-117937049-A Diaphragm and secondary battery comprising same 欣旺达动力科技股份有限公司 2024-04-26 CN claimed
CN-117776939-A Diamine containing cyclohexane and norbornane structure, preparation method and application thereof in preparation of transparent nylon 万华化学集团股份有限公司 2024-03-29 CN claimed
CN-117154342-A Polyimide lithium battery diaphragm containing benzonorbornene structure and preparation method thereof 南昌大学 2023-12-01 CN claimed
CN-116284185-A Nucleotide analogs and their use in sequencing 深圳赛陆医疗科技有限公司 2023-06-23 CN claimed
CN-116239433-A Method for preparing dibenzobicycloheptadiene in high yield 常州大学 2023-06-09 CN claimed
CN-116178203-A Polyimide containing amide bond and benzonorbornane structure and preparation method thereof 南昌大学 2023-05-30 CN claimed
CN-115991873-A Low-dielectric fluorinated aromatic polyimide film and preparation method thereof 慧创(东莞)材料技术有限责任公司 2023-04-21 CN claimed
CN-115746301-A High-transparency polyimide film containing benzonorbornene structure and preparation method thereof 慧创(东莞)材料技术有限责任公司 2023-03-07 CN claimed
CN-113388109-B Polyimide with main chain containing benzonorbornene structure and preparation method thereof 南昌大学 2023-01-31 CN claimed
US-7781615-B2 Process for the preparation of amines SYNGENTA CROP PROTECTION, INC. (US) 2010-08-24 US claimed
US-20090221856-A1 PROCESS FOR THE PREPARATION OF AMINES SYNGENTA CROP PROTECTION, INC. (US) 2009-09-03 US claimed
EP-1963251-A2 PROCESS FOR THE PREPARATION OF AMINES Syngeta Participations AG (CH) 2008-09-03 EP claimed
WO-2007068417-A2 PROCESS FOR THE PREPARATION OF AMINES SYNGENTA PARTICIPATIONS AG (CH) 2007-06-21 WO claimed
WO-1994002125-A1 METHOD FOR PREVENTING AND TREATING A VIRAL CONDITION BY INHIBITING MEMBRANE FUSION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-02-03 WO claimed
US-5198567-A BENZONORBORNENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICINAL AND COSMETIC COMPOSITIONS CONTAINING THEM L'OREAL (FR) 1993-03-30 US claimed
US-5053547-A BENZONORBORNENE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICINAL AND COSMETIC COMPOSITIONS CONTAINING THEM L'OREAL (FR) 1991-10-01 US claimed
US-4948716-A CONTAINING DEVELOPMENT INHIBITOR FUJI PHOTO FILM CO., LTD. (JP) 1990-08-14 US claimed
US-4931589-A Benzonorbornene derivatives, processes for their preparation and medicinal and cosmetic compositions containing them L'OREAL (FR) 1990-06-05 US claimed
US-4783549-A Benzonorbornene derivatives, processes for their preparation and medicinal and cosmetic compositions containing them L'OREAL (FR) 1988-11-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221856-A1 PROCESS FOR THE PREPARATION OF AMINES HRH3, PAH, C1R CHRNB4 2479/4885CHRNA3 1549/4885IDO1 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.