Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.79 |
| ▸ | TSHR | P16473 | 2/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Questiomycin B SCHEMBL6047097 | 0.92 | ALOX15 (0.83) | ALOX15TSHRHSD17B10ALDH1A1MAPT | |
| Questiomycin B SCHEMBL28102191 | 0.92 | ALOX15 (0.94) | ALOX15TSHRHSD17B10ALDH1A1MAPT | |
| SCHEMBL18612812 | 0.92 | ALOX15 (0.94) | ALOX15TSHRHSD17B10ALDH1A1MAPT | |
| Questiomycin B SCHEMBL28106010 | 0.92 | ALOX15 (0.94) | ALOX15TSHRHSD17B10ALDH1A1MAPT | |
| Questiomycin B SCHEMBL24436 | 0.89 | — | — | |
| Questiomycin B SCHEMBL3999786 | 0.89 | ALOX15 (1.00) | ALOX15TSHRHSD17B10ALDH1A1MAPT | |
| Questiomycin B SCHEMBL29430322 | 0.89 | — | — | |
| Questiomycin B SCHEMBL3887270 | 0.86 | — | — | |
| Questiomycin B SCHEMBL11330404 | 0.86 | ALOX15 (0.94) | ALOX15TSHRHSD17B10ALDH1A1MAPT | |
| Questiomycin B SCHEMBL4747619 | 0.86 | ALOX15 (0.94) | ALOX15TSHRHSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10703746-B2 | Mutant IDH1 inhibitors useful for treating cancer | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2020-07-07 | — | — | US | disclosed |
| CN-110193353-A | A kind of attapulgite and aniline-o-aminophenol compound adsorbent and preparation method thereof | 明光市飞洲新材料有限公司 | 2019-09-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10703746-B2 | Mutant IDH1 inhibitors useful for treating cancer | IDH1, IDH3B, IDH3A | ALOX15 4073/4885TSHR 4167/4885HSD17B10 926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.