Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SI | P14410 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 6/20 | 0.41 |
| ▸ | GBA1 | P04062 | 5/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22179332 | 1.00 | SI (0.45) | SIMGAMOGAGBA1TRPA1 | |
| SCHEMBL20273777 | 1.00 | SI (0.45) | SIMGAMOGAGBA1TRPA1 | |
| SCHEMBL10093807 | 1.00 | SI (0.45) | SIMGAMOGAGBA1TRPA1 | |
| SCHEMBL12868812 | 1.00 | SI (0.45) | SIMGAMOGAGBA1TRPA1 | |
| SCHEMBL19976403 | 0.98 | SI (0.48) | SIMGAMOGAGBA1TRPA1 | |
| SCHEMBL19590241 | 0.84 | SI (0.48) | SIMGAMOGAGBA1TRPA1 | |
| SCHEMBL23640158 | 0.83 | SLC5A1 (0.38) | SIMGAMOGASLC5A1SLC5A2 | |
| SCHEMBL23640081 | 0.83 | SLC5A1 (0.38) | SIMGAMOGASLC5A1SLC5A2 | |
| SCHEMBL15982394 | 0.83 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL15982409 | 0.83 | TRPA1 (0.36) | SIMGAMOGAGBA1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020140054-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. (US) | 2020-07-02 | — | — | WO | disclosed |