Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20988214 | 0.90 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3913430 | 0.81 | MEN1 (0.52) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL16609900 | 0.75 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL23228558 | 0.74 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL15427994 | 0.74 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL20618157 | 0.74 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL30902176 | 0.74 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL20980105 | 0.73 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL15374432 | 0.73 | MEN1 (0.60) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL15367247 | 0.73 | MEN1 (0.60) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020140054-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. (US) | 2020-07-02 | — | — | WO | disclosed |