SCHEMBL30902176

SCHEMBL30902176

CCOC(=O)C1CCN(C2CNC2)C1=O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 5/20 0.40
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
POLB P06746 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TLR4 O00206 1/20 0.36
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22720284 0.76 FPR2 (0.48) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL22720447 0.76 TP53 (0.51) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL3913430 0.75 MEN1 (0.52) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL22174706 0.74 MEN1 (0.51) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL31257394 0.74 TP53 (0.44) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL15427994 0.72 MEN1 (0.49) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL16609900 0.70 MEN1 (0.47) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL22724577 0.69 FPR2 (0.41) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL23228558 0.69 MEN1 (0.46) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL20988214 0.69 MEN1 (0.46) MEN1KMT2AMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117957219-A Pyridine derivative and application thereof 四川汇宇制药股份有限公司 2024-04-30 CN disclosed