Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20456544 | 0.83 | MAPT (0.63) | LMNAMAPTALDH1A1POLBKDM4E | |
| SCHEMBL29773303 | 0.83 | GFER (0.65) | AKR1C3LMNAMAPTALDH1A1CYP2C9 | |
| SCHEMBL21583811 | 0.83 | AKR1C3 (0.61) | AKR1C3LMNAMAPTALDH1A1HPGD | |
| SCHEMBL8014611 | 0.82 | ALDH1A1 (0.61) | AKR1C3LMNAMAPTALDH1A1CYP2C9 | |
| SCHEMBL24267460 | 0.82 | PANK3 (0.54) | LMNAMAPTALDH1A1HPGDHTT | |
| SCHEMBL25787603 | 0.82 | MAPT (0.61) | LMNAMAPTALDH1A1HTTGAA | |
| SCHEMBL25045164 | 0.82 | MAPT (0.56) | LMNAMAPTALDH1A1HTTGAA | |
| SCHEMBL20456543 | 0.82 | L3MBTL1 (0.68) | AKR1C3ACHEMAPTALDH1A1HTT | |
| Toluene SCHEMBL28499348 | 0.80 | KMT2A (0.57) | ACHEMAPTALDH1A1HTTPOLB | |
| SCHEMBL630856 | 0.80 | AKR1C3 (0.65) | AKR1C3LMNAMAPTALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805214-B1 | JAK3 SELECTIVE INHIBITOR | UNIV PEKING SHENZHEN GRADUATE SCHOOL (CN) | 2023-07-05 | — | — | EP | disclosed |
| EP-3805214-A1 | JAK3 SELECTIVE INHIBITOR | Peking University Shenzhen Graduate School (CN) | 2021-04-14 | — | — | EP | disclosed |
| WO-2020140055-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. (US) | 2020-07-02 | — | — | WO | disclosed |
| WO-2020140054-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. (US) | 2020-07-02 | — | — | WO | disclosed |