SCHEMBL22175152

SCHEMBL22175152

CC(C)C[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)NCC(=O)N=O

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 8/20 0.51
ANPEP P15144 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14889781 0.88 FPR2 (0.56) FPR2ANPEP
SCHEMBL20983182 0.88 FPR2 (0.56) FPR2ANPEP
SCHEMBL14890002 0.88 FPR2 (0.54) FPR2ANPEP
SCHEMBL22150345 0.88 FPR2 (0.54) FPR2ANPEP
SCHEMBL14889808 0.88 FPR2 (0.56) FPR2ANPEP
SCHEMBL22607488 0.87 FPR2 (0.53) FPR2ANPEP
SCHEMBL14889782 0.87 FPR2 (0.53) FPR2ANPEP
SCHEMBL14890192 0.84 FPR2 (0.54) FPR2ANPEP
SCHEMBL14889713 0.84 FPR2 (0.49) FPR2ANPEP
SCHEMBL14906567 0.84 FPR2 (0.56) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3078656-B1 AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN INC (US) 2020-07-01 EP disclosed