SCHEMBL22607488

SCHEMBL22607488

CC(C)CC(NC(=O)Nc1ccc(Br)cc1F)C(=O)NCC(N)=O

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 8/20 0.53
ANPEP P15144 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14889782 1.00 FPR2 (0.53) FPR2ANPEP
SCHEMBL14889713 0.96 FPR2 (0.49) FPR2ANPEP
SCHEMBL14889781 0.90 FPR2 (0.56) FPR2ANPEP
SCHEMBL22150345 0.90 FPR2 (0.54) FPR2ANPEP
SCHEMBL14890002 0.90 FPR2 (0.54) FPR2ANPEP
SCHEMBL14889808 0.90 FPR2 (0.56) FPR2ANPEP
SCHEMBL20983182 0.90 FPR2 (0.56) FPR2ANPEP
SCHEMBL14889714 0.88 FPR2 (0.58) FPR2ANPEP
SCHEMBL14902807 0.88 FPR2 (0.58) FPR2ANPEP
SCHEMBL22175152 0.87 FPR2 (0.51) FPR2ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104114164-B Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators 阿勒根公司 2016-11-16 CN claimed
EP-3795148-B1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN INC (US) 2025-06-18 EP disclosed
EP-3795148-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN, INC. (US) 2021-03-24 EP disclosed
EP-2964213-B1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN INC (US) 2020-11-04 EP disclosed