Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SHMT1 | P34896 | 3/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19110989 | 0.82 | CA1 (0.39) | CA1P2RX7ALDH1A1PIK3CDKCNJ11 | |
| SCHEMBL9112217 | 0.82 | CA1 (0.39) | KDM4CCA1P2RX7ALDH1A1NAALAD2 | |
| SCHEMBL9112225 | 0.82 | CA1 (0.39) | KDM4CCA1P2RX7ALDH1A1NAALAD2 | |
| SCHEMBL17771181 | 0.81 | CA1 (0.44) | CA1P2RX7ALDH1A1PIK3CDMMP2 | |
| SCHEMBL9088646 | 0.79 | GRM8 (0.48) | — | |
| SCHEMBL26213602 | 0.79 | KDM4C (0.42) | KDM4CALDH1A1SHMT1SHMT2PIK3CD | |
| SCHEMBL15680104 | 0.79 | ALDH1A1 (0.52) | KDM4CALDH1A1SHMT1SHMT2NAALAD2 | |
| SCHEMBL19750428 | 0.78 | CA1 (0.39) | CA1P2RX7ALDH1A1PIK3CD | |
| SCHEMBL20767063 | 0.78 | CA1 (0.35) | CA1P2RX7ALDH1A1NAALAD2PIK3CD | |
| SCHEMBL9525579 | 0.77 | ALDH1A1 (0.50) | KDM4CALDH1A1SHMT1SHMT2NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3078656-B1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-07-01 | — | — | EP | disclosed |