Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2217556 | 1.00 | GPR119 (0.36) | GPR119GPR84PRMT5WDR77HRH3 | |
| SCHEMBL2218046 | 0.93 | GPR119 (0.39) | GPR119HRH3ACACBACACARAB9A | |
| SCHEMBL2218048 | 0.93 | GPR119 (0.39) | GPR119HRH3ACACBACACARAB9A | |
| SCHEMBL2215210 | 0.92 | GPR119 (0.39) | GPR119HRH3ACACBACACARAB9A | |
| SCHEMBL2217329 | 0.92 | GPR119 (0.38) | GPR119HRH3ACACBACACARAB9A | |
| SCHEMBL2216314 | 0.92 | GPR119 (0.38) | GPR119HRH3ACACBACACARAB9A | |
| SCHEMBL2216312 | 0.92 | GPR119 (0.38) | GPR119HRH3ACACBACACARAB9A | |
| SCHEMBL2217324 | 0.92 | GPR119 (0.38) | GPR119HRH3ACACBACACARAB9A | |
| SCHEMBL2216879 | 0.90 | GPR119 (0.37) | GPR119HRH3ACACBACACARAB9A | |
| SCHEMBL2216883 | 0.90 | GPR119 (0.37) | GPR119HRH3ACACBACACARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178054-A1 | Heterocyclic GPCR Agonists | PROSIDION LIMITED (GB) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178054-A1 | Heterocyclic GPCR Agonists | GPR119, GCGR, GPR27 | GPR119 1/4885GPR84 8/4885PRMT5 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.