Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843894 | 0.90 | GPR119 (0.49) | GPR119GPR183KCNH2NR1H4 | |
| SCHEMBL1847026 | 0.90 | GPR119 (0.49) | GPR119GPR183KCNH2NR1H4 | |
| SCHEMBL2371050 | 0.90 | GPR119 (0.49) | GPR119GPR183KCNH2 | |
| SCHEMBL1843250 | 0.89 | GPR119 (0.48) | GPR119GPR183KCNH2 | |
| SCHEMBL2215847 | 0.89 | GPR119 (0.50) | GPR119GPR183KCNH2 | |
| SCHEMBL2214804 | 0.88 | GPR119 (0.47) | GPR119GPR183KCNH2 | |
| SCHEMBL2371173 | 0.86 | GPR119 (0.64) | GPR119GPR183KCNH2 | |
| SCHEMBL2371302 | 0.85 | GPR119 (0.49) | GPR119GPR183KCNH2 | |
| SCHEMBL15490275 | 0.81 | GPR119 (0.51) | GPR119GPR183KCNH2 | |
| SCHEMBL1713501 | 0.79 | GPR119 (0.45) | GPR119GPR183KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178054-A1 | Heterocyclic GPCR Agonists | PROSIDION LIMITED (GB) | 2011-07-21 | — | — | US | disclosed |
| US-20110178054-A1 | Heterocyclic GPCR Agonists | PROSIDION LIMITED (GB) | 2011-07-21 | — | — | US | disclosed |
| US-20110178054-A1 | Heterocyclic GPCR Agonists | PROSIDION LIMITED (GB) | 2011-07-21 | — | — | US | disclosed |
| WO-2010004348-A1 | HETEROCYCLIC GPCR AGONISTS | PROSIDION LIMITED (GB) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178054-A1 | Heterocyclic GPCR Agonists | GPR119, GCGR, GPR27 | GPR119 1/4885GPR183 27/4885KCNH2 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.