Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.62 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22175862 | 1.00 | L3MBTL4 (0.62) | L3MBTL4L3MBTL3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL22176104 | 0.99 | L3MBTL4 (0.63) | L3MBTL4L3MBTL3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL22175859 | 0.94 | ALDH1A1 (0.65) | L3MBTL4L3MBTL3ALDH1A1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL22164229 | 0.93 | ALDH1A1 (0.64) | L3MBTL4L3MBTL3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL24962414 | 0.92 | MAPT (0.64) | L3MBTL4L3MBTL3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL12972414 | 0.86 | MAPT (0.59) | L3MBTL1MAPTHTTHSP90AA1NPSR1 | |
| SCHEMBL22175877 | 0.85 | MAPT (0.52) | L3MBTL4L3MBTL3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL22175856 | 0.84 | ALDH1A1 (0.49) | L3MBTL4L3MBTL3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL22175848 | 0.84 | L3MBTL4 (0.51) | L3MBTL4L3MBTL3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL22176051 | 0.84 | L3MBTL4 (0.48) | L3MBTL4L3MBTL3ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138015-A1 | PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND | 大正製薬株式会社 | 2020-07-02 | — | — | WO | disclosed |