SCHEMBL22178755

SCHEMBL22178755

c1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccc(-c6c7ccccc7c(-c7ccc(-c8cccc9oc%10ccccc%10c89)c8ccccc78)c7ccccc67)c6ccccc56)c5oc6ccccc6c45)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC14B O60729 3/20 0.42
CDC14A Q9UNH5 3/20 0.42
ALOX5 P09917 2/20 0.40
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
CSF1R P07333 1/20 0.35
PDGFRB P09619 1/20 0.35
KIT P10721 1/20 0.35
FLT3 P36888 1/20 0.35
KMT2A Q03164 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
CYP19A1 P11511 2/20 0.34
CYP17A1 P05093 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GLA P06280 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20334105 0.92 CDC14B (0.41) CDC14BCDC14AALOX5MAPTMEN1
SCHEMBL23504477 0.92 ALOX5 (0.41) CDC14BCDC14AALOX5MAPTMEN1
SCHEMBL23504526 0.92 ALOX5 (0.41) CDC14BCDC14AALOX5MAPTMEN1
SCHEMBL26404171 0.91 CDC14B (0.49) CDC14BCDC14AALOX5MAPTMEN1
SCHEMBL20363665 0.91 CDC14B (0.42) CDC14BCDC14AALOX5MAPTMEN1
SCHEMBL23504707 0.91 ALOX5 (0.45) CDC14BCDC14AALOX5MAPTMEN1
SCHEMBL23504701 0.91 ALOX5 (0.45) CDC14BCDC14AALOX5MAPTMEN1
SCHEMBL21170015 0.91 CDC14B (0.43) CDC14BCDC14AALOX5MAPTMEN1
SCHEMBL22455719 0.90 CDC14B (0.39) CDC14BCDC14AALOX5MAPTMEN1
SCHEMBL18382885 0.90 CDC14B (0.41) CDC14BCDC14AALOX5MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND OR10J3, ESR1, NFE2L2 CDC14B 1578/4885CDC14A 1750/4885ALOX5 2448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.