Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.58 |
| ▸ | HTR3A | P46098 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 3/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1761623 | 0.82 | CHRNA7 (0.60) | CHRNA7HTR3ANPC1RAB9AYTHDC1 | |
| Hydrochloric Acid SCHEMBL1761864 | 0.81 | CHRNA7 (0.58) | CHRNA7HTR3ANPC1RAB9AYTHDC1 | |
| SCHEMBL2089327 | 0.81 | CHRNA7 (0.64) | CHRNA7HTR3ANPC1RAB9AYTHDC1 | |
| SCHEMBL12441910 | 0.79 | CHRNA7 (0.64) | CHRNA7HTR3ANPC1RAB9AYTHDC1 | |
| SCHEMBL2086156 | 0.79 | CHRNA7 (0.64) | CHRNA7HTR3ANPC1RAB9AYTHDC1 | |
| SCHEMBL2218695 | 0.77 | USP30 (0.41) | CHRNA7HTR3AUSP30DYRK1A | |
| Indisetron SCHEMBL332330 | 0.76 | NPC1 (0.61) | CHRNA7HTR3ANPC1RAB9AYTHDC1 | |
| Indisetron SCHEMBL18311525 | 0.76 | NPC1 (0.61) | CHRNA7HTR3ANPC1RAB9AYTHDC1 | |
| SCHEMBL7339950 | 0.76 | NPC1 (0.61) | CHRNA7HTR3ANPC1RAB9AYTHDC1 | |
| SCHEMBL7342673 | 0.76 | NPC1 (0.61) | CHRNA7HTR3ANPC1RAB9AYTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178075-A1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | XIE WENGE | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178075-A1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | CHRNA7, CHRNA5, CHRNA2 | CHRNA7 1/4885HTR3A 61/4885NPC1 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.