SCHEMBL22178802

SCHEMBL22178802

CC(C)N1CN(C(C)C)c2cc(OCCCCN3C(=O)c4ccccc4C3=O)ccc21

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 5/20 0.50
▸ MAPT P10636 3/20 0.50
▸ L3MBTL1 Q9Y468 2/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ HPGD P15428 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ MAOB P27338 4/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ NPC1 O15118 1/20 0.44
▸ DRD2 P14416 1/20 0.44
▸ DRD3 P35462 1/20 0.44
▸ MEN1 O00255 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ PRKDC P78527 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23966170 0.76 CARM1 (0.37) —
SCHEMBL12227464 0.75 HPGD (0.82) RAB9AMAPTL3MBTL1SMN1; SMN2HPGD
SCHEMBL23966192 0.75 L3MBTL1 (0.34) RAB9AL3MBTL1HPGDNPSR1MAOB
SCHEMBL10527876 0.74 RAB9A (0.61) RAB9AMAPTL3MBTL1SMN1; SMN2HPGD
SCHEMBL23742932 0.74 RAB9A (0.61) RAB9AMAPTL3MBTL1SMN1; SMN2HPGD
SCHEMBL30105286 0.74 RAB9A (0.61) RAB9AMAPTL3MBTL1SMN1; SMN2HPGD
SCHEMBL18501643 0.73 RAB9A (0.83) RAB9AMAPTSMN1; SMN2HPGDNPSR1
SCHEMBL10680921 0.73 HPGD (0.58) RAB9AMAPTL3MBTL1SMN1; SMN2HPGD
SCHEMBL7530393 0.73 RAB9A (0.60) RAB9AMAPTL3MBTL1SMN1; SMN2HPGD
SCHEMBL1999435 0.73 RAB9A (0.90) RAB9AMAPTL3MBTL1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210356461-A1 CARBENE COMPOUND, CARBENE-METAL NANOPARTICLE COMPLEX AND PREPARATION METHOD THEREOF KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2021-11-18 — — US disclosed
US-20210229104-A1 SUBSTRATE FOR NUCLEIC ACID AMPLIFICATION, AND METHOD FOR MANUFACTURING SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2021-07-29 — — US disclosed
WO-2020138982-A1 GRAPHENE CHANNEL MEMBER COMPRISING CADAVERINE OLFACTORY RECEPTOR AND SENSOR COMPRISING SAME 한국생명공학연구원 2020-07-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210356461-A1 CARBENE COMPOUND, CARBENE-METAL NANOPARTICLE COMPLEX AND PREPARATION METHOD THEREOF MB, CLTB, PARN RAB9A 806/4885MAPT 2416/4885L3MBTL1 1619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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