Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | CDA | P32320 | 6/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.32 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23906501 | 0.87 | ALDH1A1 (0.41) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL18573808 | 0.83 | ALDH1A1 (0.38) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL23906506 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL18573809 | 0.78 | ALDH1A1 (0.33) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL18852507 | 0.73 | ALDH1A1 (0.38) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL18573802 | 0.73 | ALDH1A1 (0.38) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL23750588 | 0.71 | ALDH1A1 (0.42) | ALDH1A1LMNATDP1PI4KAPI4K2B | |
| SCHEMBL24737151 | 0.70 | CDA (0.51) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL22460368 | 0.70 | CDA (0.51) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL13366846 | 0.70 | LMNA (0.47) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900679-B1 | 5-FLUOROURIDINE DERIVATIVES | BRAUN MELSUNGEN AG (DE) | 2020-07-01 | — | — | EP | disclosed |