SCHEMBL2218088

SCHEMBL2218088

c1ccc(N2CCOC2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.75
AKR1C3 P42330 2/20 0.52
PKM P14618 1/20 0.52
TSHR P16473 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
ALDH1A1 P00352 4/20 0.51
MAPT P10636 3/20 0.50
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
HTT P42858 2/20 0.50
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
RAD51 Q06609 1/20 0.49
KMO O15229 1/20 0.49
POLB P06746 1/20 0.48
AR P10275 2/20 0.47
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29259189 0.98 LMNA (0.79) LMNAAKR1C3PKMTSHRCYP2C9
SCHEMBL3948094 0.88 LMNA (0.95) LMNAAKR1C3PKMTSHRCYP2C9
SCHEMBL2555823 0.88 LMNA (0.95) LMNAAKR1C3PKMTSHRCYP2C9
SCHEMBL254812 0.88 LMNA (0.95) LMNAAKR1C3PKMTSHRCYP2C9
Hydrochloric Acid SCHEMBL9131024 0.86 LMNA (0.91) LMNAAKR1C3PKMTSHRCYP2C9
SCHEMBL13809379 0.86 LMNA (1.00) LMNAAKR1C3PKMTSHRCYP2C9
SCHEMBL4408839 0.86 LMNA (0.91) LMNAAKR1C3PKMTSHRCYP2C9
Ammonia Solution, Strong SCHEMBL4262260 0.86 LMNA (0.91) LMNAAKR1C3PKMTSHRCYP2C9
SCHEMBL184087 0.86 LMNA (0.91) LMNAAKR1C3PKMTSHRCYP2C9
SCHEMBL11203977 0.86 LMNA (1.00) LMNAAKR1C3PKMTSHRCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1751199-B1 NOVEL PHENOLIC RESINS ANGUS CHEMICAL (US) 2010-11-24 EP claimed
US-7319131-B2 Phenolic resins ANGUS CHEMICAL COMPANY (US) 2008-01-15 US claimed
JP-7017946-A None JP disclosed
CN-119431248-A Preparation method of oxazolidine-2, 4-dione compound 丽水学院 2025-02-14 CN disclosed
CN-116171280-A Casein kinase 1 delta modulators 詹森药业有限公司 2023-05-26 CN disclosed
EP-3383859-B1 1-CYANO-PYRROLIDINE DERIVATIVES AS INHIBITORS OF USP30 MISSION THERAPEUTICS LTD (GB) 2020-04-29 EP disclosed
CN-110003172-A The amides containing carbazole, carbamates and ureas as cryptochrome regulator 同步制药公司 2019-07-12 CN disclosed
CN-106045969-B A kind of synthetic method of the card than replacing Buddhist nun 湖南欧亚药业有限公司 2019-04-12 CN disclosed
CN-106458891-B Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators 同步制药公司 2019-04-09 CN disclosed
CN-108948043-A Novel method of the preparation for the compound for the treatment of cancer 埃克塞里艾克西斯公司 2018-12-07 CN disclosed
US-20120142853-A1 NOVEL PHENOLIC RESINS SWEDO RAYMOND J (US) 2012-06-07 US disclosed
US-4309436-A 3'(3,5-Dichlorophenyl)-spiro(3-oxabicycloc[3.1.0]hexane)-6,5'-oxazolidine-2',4'-dione CIBA-GEIGY CORPORATION (US) 1982-01-05 US disclosed
US-4198506-A INTERMEDIATES FOR THE CORRESPONDING 3-SUBSTITUTED 3-CEPHEM-4-CARBOXYLIC ACIDS BRISTOL-MYERS COMPANY (US) 1980-04-15 US disclosed
US-4180658-A ANTIBIOTICS, BACTERICIDES BRISTOL-MYERS COMPANY (US) 1979-12-25 US disclosed
US-4151352-A CEPHALOSPORINS, BACTERICIDES BRISTOL-MYERS COMPANY (US) 1979-04-24 US disclosed
US-4138554-A 7-[D-α-(4-Hydroxy-1,5-naphthyridine-3-carboxamido)-α-phenyl (and p-hydroxyphenyl)acetamido]-3-carbamoyloxymethyl-3-cephem-4-carboxylic acids BRISTOL-MYERS COMPANY (US) 1979-02-06 US disclosed
US-4112228-A BACTERICIDES BRISTOL-MYERS COMPANY (US) 1978-09-05 US disclosed
US-4104469-A CEPHALOSPORINS BRISTOL-MYERS COMPANY (US) 1978-08-01 US disclosed
US-4103085-A CEPHALOSPORIN ANTIBIOTICS BRISTOL-MYERS COMPANY (US) 1978-07-25 US disclosed
US-4082912-A ANTIBACTERIAL BRISTOL-MYERS COMPANY (US) 1978-04-04 US disclosed