Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.91 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMO | O15229 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254812 | 0.97 | LMNA (0.95) | LMNAAKR1C3PKMTSHRCYP2C9 | |
| SCHEMBL3948094 | 0.97 | LMNA (0.95) | LMNAAKR1C3PKMTSHRCYP2C9 | |
| SCHEMBL2555823 | 0.97 | LMNA (0.95) | LMNAAKR1C3PKMTSHRCYP2C9 | |
| SCHEMBL11203977 | 0.95 | LMNA (1.00) | LMNAAKR1C3PKMTSHRCYP2C9 | |
| Hydrochloric Acid SCHEMBL9131024 | 0.95 | LMNA (0.91) | LMNAAKR1C3PKMTSHRCYP2C9 | |
| SCHEMBL13809379 | 0.95 | LMNA (1.00) | LMNAAKR1C3PKMTSHRCYP2C9 | |
| Ammonia Solution, Strong SCHEMBL4262260 | 0.95 | LMNA (0.91) | LMNAAKR1C3PKMTSHRCYP2C9 | |
| SCHEMBL4408839 | 0.95 | LMNA (0.91) | LMNAAKR1C3PKMTSHRCYP2C9 | |
| SCHEMBL10070835 | 0.95 | LMNA (1.00) | LMNAAKR1C3PKMTSHRCYP2C9 | |
| SCHEMBL10070687 | 0.95 | LMNA (1.00) | LMNAAKR1C3PKMTSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2868659-B1 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-04 | — | — | EP | claimed |
| US-9181217-B2 | Method for producing optically active naphthalene compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-11-10 | — | — | US | claimed |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-06-04 | — | — | US | claimed |
| EP-2868659-A1 | Method for producing optically active naphthalene compound | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-05-06 | — | — | EP | claimed |
| EP-2749558-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2014-07-02 | — | — | EP | claimed |
| US-8637703-B2 | Methods for synthesizing ammonia borane | THE OHIO STATE UNIVERSITY (US) | 2014-01-28 | — | — | US | claimed |
| US-20130237708-A1 | Optically Active Cyclic Alcohol Compound And Method For Preparing The Same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-09-12 | — | — | US | claimed |
| EP-2007743-B1 | METHODS FOR SYNTHESIZING AMMONIA BORANE | UNIV OHIO STATE (US) | 2013-06-12 | — | — | EP | claimed |
| EP-1944291-B1 | Optically active cyclic alcohol compound and method for producing same | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-06-13 | — | — | EP | claimed |
| US-20120014857-A1 | METHODS FOR SYNTHESIZING AMMONIA BORANE | THE OHIO STATE UNIVERSITY (US) | 2012-01-19 | — | — | US | claimed |
| US-7977508-B2 | Methods for synthesizing ammonia borane | THE OHIO STATE UNIVERSITY (US) | 2011-07-12 | — | — | US | claimed |
| US-20100152451-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-06-17 | — | — | US | claimed |
| US-20090104102-A1 | METHODS FOR SYNTHESIZING AMMONIA BORANE | THE OHIO STATE UNIVERSITY | 2009-04-23 | — | — | US | claimed |
| EP-2007743-A2 | METHODS FOR SYNTHESIZING AMMONIA BORANE | The Ohio State University (US) | 2008-12-31 | — | — | EP | claimed |
| EP-1944291-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-16 | — | — | EP | claimed |
| WO-2007120511-A2 | METHODS FOR SYNTHESIZING AMMONIA BORANE | THE OHIO STATE UNIVERSITY (US) | 2007-10-25 | — | — | WO | claimed |
| US-20050173254-A1 | Nickel cobalt boron ternary alloys | TASKEM, INC. | 2005-08-11 | — | — | US | claimed |
| US-6875866-B2 | Process for synthesis of D1 receptor antagonists | SCHERING CORPORATION (US) | 2005-04-05 | — | — | US | claimed |
| US-20030199690-A1 | Process for synthesis of D1 receptor antagonists | SCHERING CORPORATION | 2003-10-23 | — | — | US | claimed |
| US-4243803-A | Production of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid | BRISTOL-MYERS COMPANY (US) | 1981-01-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199690-A1 | Process for synthesis of D1 receptor antagonists | OPRL1, AVPR1A, AVPR1B | LMNA 3842/4885AKR1C3 432/4885PKM 1574/4885 |
| US-20150152082-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | HRH1, HRH4, RB1 | LMNA 4020/4885AKR1C3 253/4885PKM 3525/4885 |
| US-20100152451-A1 | OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME | ADH1C, ADH1A, ADH5 | LMNA 1803/4885AKR1C3 23/4885PKM 393/4885 |
| US-20130237708-A1 | Optically Active Cyclic Alcohol Compound And Method For Preparing The Same | ADH1C, ADH1A, ADH5 | LMNA 1803/4885AKR1C3 23/4885PKM 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.