Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 8/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2217202 | 0.96 | HDAC4 (0.42) | HDAC4HDAC6ACACBACACAGPR119 | |
| SCHEMBL2217692 | 0.95 | HDAC4 (0.48) | HDAC4HDAC6GPR119HDAC1 | |
| SCHEMBL2217895 | 0.93 | ACACB (0.44) | HDAC4HDAC6ACACBACACAGPR119 | |
| SCHEMBL2215455 | 0.92 | ACACB (0.44) | HDAC4HDAC6ACACBACACAGPR119 | |
| SCHEMBL2218683 | 0.91 | GPR119 (0.38) | HDAC4HDAC6ACACBACACAGPR119 | |
| SCHEMBL2218651 | 0.91 | ACACB (0.42) | ACACBACACAGPR119HRH3 | |
| SCHEMBL2214951 | 0.89 | GPR119 (0.41) | HDAC4HDAC6ACACBACACAGPR119 | |
| SCHEMBL2217348 | 0.89 | ACACB (0.45) | ACACBACACAGPR119 | |
| SCHEMBL1842679 | 0.89 | HRH3 (0.44) | ACACBACACAGPR119HRH3 | |
| SCHEMBL2217000 | 0.89 | GPR119 (0.42) | HDAC4HDAC6ACACBACACAGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178054-A1 | Heterocyclic GPCR Agonists | PROSIDION LIMITED (GB) | 2011-07-21 | — | — | US | disclosed |
| US-20110178054-A1 | Heterocyclic GPCR Agonists | PROSIDION LIMITED (GB) | 2011-07-21 | — | — | US | disclosed |
| US-20110178054-A1 | Heterocyclic GPCR Agonists | PROSIDION LIMITED (GB) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178054-A1 | Heterocyclic GPCR Agonists | GPR119, GCGR, GPR27 | HDAC4 2047/4885HDAC6 1981/4885ACACB 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.