SCHEMBL2218290

SCHEMBL2218290

CC(=O)N(Cc1ccc(N(C)C)cc1)Cc1ccc(N(C)C)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.59
MEN1 O00255 1/20 0.59
GFER P55789 1/20 0.54
MAPT P10636 8/20 0.50
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.50
CYP3A4 P08684 1/20 0.50
MAPK1 P28482 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CNR2 P34972 1/20 0.48
TP53 P04637 3/20 0.47
HPGD P15428 1/20 0.47
HDAC1 Q13547 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24723659 0.84 ALDH1A1 (0.59) KMT2AMEN1GFERMAPTALDH1A1
SCHEMBL30945859 0.79 KMT2A (0.54) KMT2AMEN1GFERMAPTALDH1A1
SCHEMBL9416644 0.79 ALDH1A1 (0.50) ALDH1A1CYP3A4TP53HSD17B10
SCHEMBL595605 0.78 KMT2A (0.57) KMT2AMEN1GFERMAPTALDH1A1
SCHEMBL6414624 0.78 MEN1 (0.56) KMT2AMEN1ALDH1A1CNR2
SCHEMBL6078000 0.78 LMNA (0.55) KMT2AMEN1MAPTALDH1A1TDP1
SCHEMBL627450 0.78 MAPT (0.44) KMT2AMEN1GFERMAPTALDH1A1
SCHEMBL2117209 0.77 LMNA (0.62) KMT2AMEN1ALDH1A1TSHRMAPK1
SCHEMBL10045689 0.75 KMT2A (0.54) KMT2AMEN1GFERMAPTALDH1A1
SCHEMBL2862421 0.75 ALDH1A1 (0.54) KMT2AMEN1MAPTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2666814-B1 ELECTRICALLY CONDUCTIVE RUBBER ELASTOMER, CHARGING MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2018-03-14 EP disclosed
EP-2490077-B1 ELECTRIFICATING MEMBER AND ELECTROPHOTOGRAPHIC DEVICE CANON KK (JP) 2014-10-01 EP disclosed
US-8750762-B2 Charging member with vulcanized rubber, and electrophotographic apparatus including the charging member CANON KABUSHIKI KAISHA (JP) 2014-06-10 US disclosed
EP-2666814-A1 ELECTRICALLY CONDUCTIVE RUBBER ELASTOMER, CHARGING MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS Canon Kabushiki Kaisha (JP) 2013-11-27 EP disclosed
US-8491994-B2 Conductive rubber elastic material, charging member and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-07-23 US disclosed
US-20120224887-A1 CONDUCTIVE RUBBER ELASTIC MATERIAL, CHARGING MEMBER AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-09-06 US disclosed
EP-2490077-A1 ELECTRIFICATING MEMBER AND ELECTROPHOTOGRAPHIC DEVICE Canon Kabushiki Kaisha (JP) 2012-08-22 EP disclosed
US-20110176833-A1 CHARGING MEMBER AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-07-21 US disclosed