Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22184132 | 0.88 | MTNR1A (0.44) | MTNR1AMTNR1BMEN1POLBKMT2A | |
| SCHEMBL22184151 | 0.85 | MTNR1A (0.42) | MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL25814254 | 0.84 | MTNR1A (0.42) | MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL22184085 | 0.83 | POLB (0.41) | POLB | |
| SCHEMBL25816016 | 0.82 | BCHE (0.37) | POLB | |
| SCHEMBL22184128 | 0.80 | POLB (0.39) | POLB | |
| SCHEMBL20570535 | 0.75 | HPGD (0.46) | HPGDKMT2A | |
| SCHEMBL20570855 | 0.74 | RXFP1 (0.41) | POLB | |
| SCHEMBL23112155 | 0.70 | MTNR1A (0.64) | MTNR1AMTNR1B | |
| SCHEMBL3342032 | 0.70 | PTGS2 (0.37) | MEN1POLBHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200206359-A1 | Method And Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206359-A1 | Method And Molecules | PAICS, EPCAM, SQLE | MTNR1A 2468/4885MTNR1B 2502/4885MEN1 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.