Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17808316 | 0.78 | CA1 (0.36) | SQORALDH1A1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL17816256 | 0.77 | SQOR (0.33) | SQORALDH1A1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL15823124 | 0.76 | ALDH1A1 (0.34) | SQORALDH1A1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL17808315 | 0.73 | ALDH1A1 (0.32) | SQORALDH1A1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL22199007 | 0.72 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL24299457 | 0.68 | — | — | |
| SCHEMBL22185957 | 0.68 | ALDH1A1 (0.34) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9967856 | 0.67 | PIK3CA (0.39) | CYP1A2CYP2C19 | |
| SCHEMBL15244133 | 0.66 | ALDH1A1 (0.39) | SQORALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL16466586 | 0.65 | ALDH1A1 (0.32) | ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206233-A1 | HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS | IDH1, IDH2, IDH3A | SQOR 96/4885ALDH1A1 149/4885CYP1A2 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.