Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25777990 | 0.76 | KMO (0.45) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL26536722 | 0.74 | KMO (0.35) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL22186207 | 0.73 | — | — | |
| SCHEMBL23750310 | 0.73 | KMO (0.49) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL19651317 | 0.72 | KMO (0.41) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL22248190 | 0.72 | L3MBTL1 (0.43) | KMOPRSS1PRSS2PRSS3MAPT | |
| SCHEMBL25467893 | 0.71 | KMO (0.42) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL21207823 | 0.71 | PRSS1 (0.45) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL22137862 | 0.70 | KMO (0.48) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL19296844 | 0.69 | KMO (0.52) | KMOPRSS1PRSS2PRSS3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3674290-A2 | HETEROCYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND | Samsung Electronics Co., Ltd. (KR) | 2020-07-01 | — | — | EP | disclosed |