Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | KDM5A | P29375 | 1/20 | 0.65 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.65 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606159 | 0.84 | ALDH1A1 (0.51) | KDM4EKDM5AJMJD1CKDM3AADORA1 | |
| SCHEMBL22186826 | 0.83 | KDM4E (0.69) | KDM4EKDM5AJMJD1CKDM3AADORA1 | |
| SCHEMBL20832737 | 0.81 | CDC7 (0.44) | KDM4EKDM5AJMJD1CKDM3AADORA1 | |
| SCHEMBL20832590 | 0.81 | CDC7 (0.44) | KDM4EKDM5AJMJD1CKDM3AADORA1 | |
| SCHEMBL19699460 | 0.79 | L3MBTL1 (0.51) | KDM4EADORA1CDC7LMNAMEN1 | |
| SCHEMBL18943862 | 0.79 | KDM4E (1.00) | KDM4EKDM5AJMJD1CKDM3AALDH1A1 | |
| SCHEMBL22186831 | 0.79 | KDM4E (0.63) | KDM4EKDM5AJMJD1CKDM3AADORA1 | |
| SCHEMBL28891555 | 0.77 | ADORA1 (0.45) | KDM4EKDM5AJMJD1CKDM3AADORA1 | |
| SCHEMBL15358651 | 0.77 | ADORA1 (0.45) | KDM4EKDM5AJMJD1CKDM3AADORA1 | |
| SCHEMBL28891554 | 0.77 | ADORA1 (0.45) | KDM4EKDM5AJMJD1CKDM3AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138271-A1 | HETEROCYCLIC DERIVATIVES AS Nav1.7 and Nav1.8 BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2020-07-02 | — | — | WO | disclosed |