SCHEMBL2218654

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2219867	0.86	CASR (0.59)	CASRHTR1ASLC6A2OPRM1DRD3
	SCHEMBL2217426	0.82	CASR (0.50)	CASRHTTHTR1AADRA2AADORA3
	Hydrochloric Acid SCHEMBL2837888	0.77	KDM4E (0.41)	MEN1KMT2ASMN1; SMN2HTTCYP3A4
	SCHEMBL13384263	0.75	ADORA3 (0.38)	MEN1KMT2ASMN1; SMN2HTTADORA3
	SCHEMBL14469653	0.75	CASR (0.56)	MEN1KMT2ACASRSMN1; SMN2HTT
	SCHEMBL2780530	0.74	POLB (0.41)	MEN1KMT2ASMN1; SMN2ADORA3CYP1A2
	SCHEMBL17622	0.72	CXCR2 (0.42)	MEN1KMT2ASMN1; SMN2HTTALDH1A1
	SCHEMBL2217384	0.71	HPGD (0.56)	CASRSMN1; SMN2HTTLMNADRD3
	SCHEMBL3657245	0.71	HPGD (0.56)	CASRSMN1; SMN2HTTLMNADRD3
	SCHEMBL672597	0.71	NOTUM (0.42)	MEN1KMT2ACYP1A2CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.