SCHEMBL221874

SCHEMBL221874

CC(=Cc1ccc(N(C)C)cc1)C(N)=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.53
ALDH1A1 P00352 6/20 0.53
KMT2A Q03164 5/20 0.53
MEN1 O00255 4/20 0.53
LMNA P02545 2/20 0.53
JAK2 O60674 1/20 0.53
MITF O75030 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53
NTSR1 P30989 1/20 0.53
CYP2C19 P33261 1/20 0.53
HDAC3 O15379 1/20 0.53
HDAC4 P56524 1/20 0.53
HDAC1 Q13547 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC10 Q969S8 1/20 0.53
HDAC11 Q96DB2 1/20 0.53
HDAC8 Q9BY41 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5830527 0.86 AKR1C3 (0.52) MAPTALDH1A1KMT2AMEN1CYP2C9
SCHEMBL5830531 0.86 AKR1C3 (0.52) MAPTALDH1A1KMT2AMEN1CYP2C9
SCHEMBL10978901 0.85 HDAC3 (0.60) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL10978899 0.85 HDAC3 (0.60) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL5950256 0.83 AKR1C3 (0.62) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL5950254 0.83 AKR1C3 (0.62) MAPTALDH1A1KMT2AMEN1LMNA
Guanidine SCHEMBL8517217 0.82 AKR1C3 (0.51) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL5436222 0.82 SLC9A3 (0.60) MAPTALDH1A1KMT2AMEN1LMNA
Guanidine SCHEMBL8517216 0.82 AKR1C3 (0.51) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL222105 0.81 ALDH1A1 (0.64) MAPTALDH1A1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10222721-B2 Urethane foam and toner-conveying roller using the same BRIDGESTONE CORPORATION (JP) 2019-03-05 US disclosed
US-9563154-B2 Toner transfer roller and image forming device using the same BRIDGESTONE CORPORATION (JP) 2017-02-07 US disclosed
US-9316958-B2 Charge-controlled polyurethane foam and toner-conveying roller using the same BRIDGESTONE CORPORATION (JP) 2016-04-19 US disclosed
US-8999620-B2 Toner for electrostatic latent image development KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2015-04-07 US disclosed
US-8999619-B2 Toner for electrostatic latent image development KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2015-04-07 US disclosed
US-8980514-B2 Toner for electrostatic latent image development KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2015-03-17 US disclosed
US-20140030649-A1 TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2014-01-30 US disclosed
US-8088876-B2 Copolymer, resin for electrophotographic functional component parts, developing roller, and electrophotographic apparatus CANON KASEI KABUSHIKI KAISHA (JP) 2012-01-03 US disclosed
US-20110188900-A1 URETHANE FOAM AND TONER-CONVEYING ROLLER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-08-04 US disclosed
US-20110177926-A1 CHARGE-CONTROLLED POLYURETHANE FOAM AND TONER-CONVEYING ROLLER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-07-21 US disclosed
US-20100158579-A1 TONER TRANSFER ROLLER AND IMAGE FORMING DEVICE USING THE SAME BRIDGESTONE CORPORATION (JP) 2010-06-24 US disclosed
EP-1178360-B1 ELECTROPHOTOGRAPHING DRY-TYPE TONER AND PRODUCTION METHOD THEREFOR SEIKO EPSON CORP (JP) 2006-11-15 EP disclosed
US-6806011-B2 MICROSTRUCTURE PARTICLES COMPRISING COLORED POLYMERS, RELEASE AGENTS, BINDERS AND COATINGS, HAVING OFFSET RESISTANCE, DURABILITY AND RADIATION TRANSPARENT; ELECTROGRAPHY SEIO EPSON CORPORATION (JP) 2004-10-19 US disclosed
US-20040110078-A1 Dry toner for electrophotography, and its production process SEIKO EPSON CORPORATION 2004-06-10 US disclosed
US-6686112-B2 MIXTURE OF COLORED PARTICLES, RELEASE AGENTS AND POLYMER RESIN; OFFSET RESISTANCE SEIKO EPSON CORPORATION (JP) 2004-02-03 US disclosed
US-20020160289-A1 Electrophotographing dry-type toner and production method therefor SEIKO EPSON CORPORATION (JP) 2002-10-31 US disclosed
EP-1178360-A1 ELECTROPHOTOGRAPHING DRY-TYPE TONER AND PRODUCTION METHOD THEREFOR SEIKO EPSON CORPORATION (JP) 2002-02-06 EP disclosed
US-4761358-A Electrostatographic encapsulated toner FUJI PHOTO FILM CO., LTD. (JP) 1988-08-02 US disclosed