Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5950254 | 1.00 | AKR1C3 (0.62) | AKR1C3MAPTALDH1A1KMT2ALMNA | |
| Guanidine SCHEMBL8517216 | 0.90 | AKR1C3 (0.51) | AKR1C3MAPTALDH1A1KMT2ALMNA | |
| Guanidine SCHEMBL8517217 | 0.90 | AKR1C3 (0.51) | AKR1C3MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL10978899 | 0.86 | HDAC3 (0.60) | MAPTALDH1A1KMT2ALMNAGAA | |
| SCHEMBL10978901 | 0.86 | HDAC3 (0.60) | MAPTALDH1A1KMT2ALMNAGAA | |
| SCHEMBL2462984 | 0.85 | AKR1C3 (0.82) | AKR1C3ALDH1A1L3MBTL1 | |
| SCHEMBL2462983 | 0.85 | AKR1C3 (0.82) | AKR1C3ALDH1A1L3MBTL1 | |
| SCHEMBL221874 | 0.83 | MAPT (0.53) | MAPTALDH1A1KMT2ALMNAGAA | |
| SCHEMBL4005429 | 0.82 | MAPT (0.61) | MAPTALDH1A1KMT2ALMNAGAA | |
| SCHEMBL11673262 | 0.81 | AKR1C3 (0.69) | AKR1C3MAPTALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060084176-A1 | Detection of uronium salts | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-04-20 | — | — | US | claimed |
| EP-0755919-B1 | Substituted cinnamic acid guanidides, process for their preparation, their use as cardiovascualr medicament or diagnostic agent, as well as medicament containing them | HOECHST AG (DE) | 1999-11-17 | — | — | EP | claimed |
| US-5883133-A | CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | claimed |
| US-8999620-B2 | Toner for electrostatic latent image development | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-8999619-B2 | Toner for electrostatic latent image development | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-8980514-B2 | Toner for electrostatic latent image development | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20140030649-A1 | TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2014-01-30 | — | — | US | disclosed |
| US-20060084176-A1 | Detection of uronium salts | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-04-20 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-5883133-A | CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| EP-0635536-B1 | Multilayered composite systems | ROEHM GMBH (DE) | 1998-04-29 | — | — | EP | disclosed |
| US-5639584-A | WET PROCESSING; AGGREGATION; PULVERIZATION IN HIGH SPEED AIR STREAM | MINOLTA CAMERA KABUSHIKI KAISHA (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0477726-B1 | Ternary mixtures of polymers | ROEHM GMBH (DE) | 1997-03-12 | — | — | EP | disclosed |
| EP-0635536-A1 | Multilayered composite systems | Röhm GmbH (DE) | 1995-01-25 | — | — | EP | disclosed |
| US-5374487-A | Compatible polymeric mixtures | ROHM GMBH (DE) | 1994-12-20 | — | — | US | disclosed |
| US-5250623-A | Compatible polymeric mixtures | ROHM GMBH (DE) | 1993-10-05 | — | — | US | disclosed |
| EP-0477726-A1 | Ternary mixtures of polymers | RÖHM GMBH (DE) | 1992-04-01 | — | — | EP | disclosed |
| WO-1991011490-A1 | COMPATIBLE POLYARYLACRYLATE AND POLYESTER MIXTURES | RÖHM GMBH (DE) | 1991-08-08 | — | — | WO | disclosed |
| EP-0440034-A1 | Compatible polymer blends | RÖHM GMBH (DE) | 1991-08-07 | — | — | EP | disclosed |