SCHEMBL22187488

SCHEMBL22187488

Cc1ccc(S(=O)(=O)Oc2cccc(NC(=O)Nc3cccc(OS(=O)(=O)c4ccc(C)cc4)c3)c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR17 Q13304 4/20 0.57
▸ CA2 P00918 1/20 0.53
▸ ENPP2 Q13822 3/20 0.52
▸ MAPT P10636 5/20 0.52
▸ NPSR1 Q6W5P4 3/20 0.52
▸ GAA P10253 1/20 0.52
▸ G6PD P11413 1/20 0.52
▸ MEN1 O00255 3/20 0.51
▸ KMT2A Q03164 3/20 0.51
▸ LMNA P02545 3/20 0.51
▸ TSHR P16473 2/20 0.51
▸ ALDH1A1 P00352 1/20 0.51
▸ ALOX15 P16050 1/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ P2RY2 P41231 2/20 0.50
▸ TP53 P04637 2/20 0.50
▸ NPC1 O15118 1/20 0.50
▸ RAB9A P51151 1/20 0.50
▸ HTT P42858 2/20 0.49
▸ POLB P06746 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29620122 1.00 GPR17 (0.57) GPR17CA2ENPP2MAPTNPSR1
SCHEMBL22187158 0.96 GPR17 (0.54) GPR17CA2ENPP2MAPTNPSR1
SCHEMBL30540135 0.96 GPR17 (0.54) GPR17CA2ENPP2MAPTNPSR1
SCHEMBL31058590 0.96 GPR17 (0.56) GPR17CA2ENPP2MAPTNPSR1
SCHEMBL21753701 0.96 GPR17 (0.56) GPR17CA2ENPP2MAPTNPSR1
SCHEMBL22187133 0.95 GPR17 (0.53) GPR17CA2ENPP2MAPTNPSR1
SCHEMBL29673656 0.95 ENPP2 (0.60) GPR17CA2ENPP2MAPTMEN1
SCHEMBL22187545 0.95 ENPP2 (0.60) GPR17CA2ENPP2MAPTMEN1
SCHEMBL30540129 0.95 GPR17 (0.53) GPR17CA2ENPP2MAPTNPSR1
SCHEMBL22187264 0.94 GPR17 (0.57) GPR17CA2ENPP2MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4253075-B1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SANKO CO LTD (JP) 2025-10-15 — — EP disclosed
US-12246549-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2025-03-11 — — US disclosed
US-12053997-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2024-08-06 — — US disclosed
US-20240190816-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SANKO CO., LTD. (JP) 2024-06-13 — — US disclosed
US-20240190156-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2024-06-13 — — US disclosed
US-11945769-B2 N,N′-diarylurea derivative, manufacturing method thereof, and thermosensitive recording material using same SANKO CO., LTD. (JP) 2024-04-02 — — US disclosed
WO-2024048448-A1 HEAT SENSITIVE RECORDING BODY 大阪シーリング印刷株式会社 2024-03-07 — — WO disclosed
EP-4253075-A2 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME Sanko Co., Ltd. (JP) 2023-10-04 — — EP disclosed
EP-3677569-A9 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME Sanko Co., Ltd. (JP) 2023-08-23 — — EP disclosed
US-20230144275-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2023-05-11 — — US disclosed
US-20230027721-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2023-01-26 — — US disclosed
WO-2023276499-A1 THERMOSENSITIVE RECORDING MATERIAL 日華化学株式会社 2023-01-05 — — WO disclosed
US-20210340099-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SANKO CO., LTD. (JP) 2021-11-04 — — US disclosed
EP-3677569-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME Sanko Co., Ltd. (JP) 2020-07-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11945769-B2 N,N′-diarylurea derivative, manufacturing method thereof, and thermosensitive recording material using same SCN1A, SCN1B, NAAA GPR17 1134/4885CA2 835/4885ENPP2 3718/4885
US-20210340099-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SCN1A, SCN1B, NAAA GPR17 1115/4885CA2 805/4885ENPP2 3676/4885
US-20240190816-A1 N,N'-DIARYLUREA DERIVATIVE, MANUFACTURING METHOD THEREOF, AND THERMOSENSITIVE RECORDING MATERIAL USING SAME SCN1A, SCN1B, SCN2A GPR17 1277/4885CA2 763/4885ENPP2 2644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback