SCHEMBL22187702

SCHEMBL22187702

Cc1cc(C2(c3ccc(OCCO)c(C)c3)c3ccc(-c4ccccc4)cc3-c3cc(-c4ccccc4)ccc32)ccc1OCCO

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 10/20 0.44
PPARG P37231 2/20 0.41
PPARA Q07869 2/20 0.41
PPARD Q03181 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.40
RARA P10276 3/20 0.40
RARB P10826 3/20 0.40
RARG P13631 3/20 0.40
MCHR1 Q99705 1/20 0.39
HTR7 P34969 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29609097 1.00 SLC6A9 (0.44) SLC6A9PPARGPPARAPPARDESR1
SCHEMBL29609205 0.90 SLC6A9 (0.41) SLC6A9PPARGPPARAPPARDESR1
SCHEMBL22187695 0.90 SLC6A9 (0.41) SLC6A9PPARGPPARAPPARDESR1
SCHEMBL22187717 0.90 ESR1 (0.39) SLC6A9PPARGPPARAPPARDESR1
SCHEMBL22187732 0.89 SLC6A9 (0.49) SLC6A9RARARARBRARGHTR7
SCHEMBL29608012 0.89 SLC6A9 (0.49) SLC6A9RARARARBRARGHTR7
SCHEMBL346226 0.86 ESR1 (0.56) PPARGPPARAPPARDESR1ESR2
SCHEMBL29385692 0.86 ESR1 (0.56) PPARGPPARAPPARDESR1ESR2
SCHEMBL30314588 0.86 ESR1 (0.56) PPARGPPARAPPARDESR1ESR2
SCHEMBL22187644 0.84 SLC6A9 (0.41) SLC6A9PPARGPPARAPPARDESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3677614-B1 THERMOPLASTIC RESIN AND OPTICAL MEMBER TEIJIN LTD (JP) 2026-05-27 EP disclosed
US-12441880-B2 Poly(ester)carbonate and method for producing poly(ester)carbonate TEIJIN LIMITED (JP) 2025-10-14 US disclosed
EP-3733734-B1 POLY(ESTER)CARBONATE AND METHOD FOR PRODUCING POLY(ESTER)CARBONATE TEIJIN LTD (JP) 2024-03-06 EP disclosed
US-20230051676-A1 POLYCARBONATE AND METHOD FOR PRODUCING POLYCARBONATE TEIJIN LIMITED (JP) 2023-02-16 US disclosed
US-11505698-B2 Polyester carbonate and method for producing polyester carbonate TEIJIN LIMITED (JP) 2022-11-22 US disclosed
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same TEIJIN LIMITED (JP) 2022-05-24 US disclosed
US-11261294-B2 Thermoplastic resin and optical member TEIJIN LIMITED (JP) 2022-03-01 US disclosed
US-20210371650-A1 POLY(ESTER)CARBONATE AND METHOD FOR PRODUCING POLY(ESTER)CARBONATE TEIJIN LIMITED (JP) 2021-12-02 US disclosed
US-20210147621-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER TEIJIN LIMITED (JP) 2021-05-20 US disclosed
CN-112175178-A Polycarbonate and preparation method and application thereof 万华化学集团股份有限公司 2021-01-05 CN disclosed
EP-3747856-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME Teijin Limited (JP) 2020-12-09 EP disclosed
US-20200354517-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME TEIJIN LIMITED (JP) 2020-11-12 US disclosed
EP-3733734-A1 POLY(ESTER)CARBONATE AND METHOD FOR PRODUCING POLY(ESTER)CARBONATE Teijin Limited (JP) 2020-11-04 EP disclosed
EP-3677614-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER Teijin Limited (JP) 2020-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354517-A1 COMPOUND HAVING FLUORENE SKELETON, AND METHOD FOR MANUFACTURING SAME RFT1, AFF1, RER1 SLC6A9 4638/4885PPARG 2369/4885PPARA 1428/4885
US-11339249-B2 Compound having fluorene skeleton, and method for manufacturing same RFT1, AFF1, RER1 SLC6A9 4638/4885PPARG 2369/4885PPARA 1428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.