Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 5/20 | 0.57 |
| ▸ | GCGR | P47871 | 5/20 | 0.57 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.57 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 4/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17654426 | 0.82 | SMN1; SMN2 (0.44) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL482405 | 0.82 | TNKS (0.46) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL11516210 | 0.80 | MAPK13 (0.53) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL28158811 | 0.78 | MAPK13 (0.86) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL23758282 | 0.78 | GAA (0.58) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL11516204 | 0.77 | MAPK14 (0.36) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL20425291 | 0.75 | MAPK13 (0.60) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL13115539 | 0.75 | MAPK14 (0.60) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL14045570 | 0.74 | MAPK13 (0.85) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL9196324 | 0.74 | MAPK11 (0.69) | MAPK13GCGRMAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10941114-B2 | Small molecule lipid II inhibitors | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2021-03-09 | — | — | US | disclosed |
| US-10941114-B2 | Small molecule lipid II inhibitors | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2021-03-09 | — | — | US | disclosed |
| US-20200216394-A1 | Small Molecule Lipid II Inhibitors | UNIVERSITY OF MARYLAND, BALTIMORE | 2020-07-09 | — | — | US | disclosed |
| US-20200216394-A1 | Small Molecule Lipid II Inhibitors | UNIVERSITY OF MARYLAND, BALTIMORE | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200216394-A1 | Small Molecule Lipid II Inhibitors | DBI, FABP2, HDLBP | MAPK13 1858/4885GCGR 2841/4885MAPK12 2944/4885 |
| US-10941114-B2 | Small molecule lipid II inhibitors | DBI, FABP2, SREBF2 | MAPK13 1750/4885GCGR 3386/4885MAPK12 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.