Sugi Predict

Sugi Predict / Compounds / SCHEMBL11516210

SCHEMBL11516210

SCHEMBL11516210

Cc1nc(-c2ccccc2)[nH]c1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK13 O15264 3/20 0.53
▸ MAPK12 P53778 3/20 0.53
▸ MAPK11 Q15759 3/20 0.53
▸ MAPK14 Q16539 3/20 0.53
▸ RAF1 P04049 2/20 0.53
▸ MAPK9 P45984 1/20 0.53
▸ GAA P10253 5/20 0.52
▸ NPC1 O15118 1/20 0.52
▸ RAB9A P51151 1/20 0.52
▸ GCGR P47871 1/20 0.51
▸ NOX1 Q9Y5S8 1/20 0.51
▸ KDM4E B2RXH2 5/20 0.50
▸ HPGD P15428 4/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ ALDH1A1 P00352 4/20 0.49
▸ GLA P06280 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ POLB P06746 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23758282 0.93 GAA (0.58) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL13115539 0.89 MAPK14 (0.60) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL20425291 0.89 MAPK13 (0.60) MAPK13MAPK12MAPK11MAPK14RAF1
Hydrochloric Acid SCHEMBL23736210 0.88 MAPK13 (0.58) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL20445285 0.87 MAPT (0.64) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL13528420 0.87 NPY5R (0.57) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL20445346 0.86 NPC1 (0.56) MAPK14NPC1RAB9AKDM4EHPGD
Hydrochloric Acid SCHEMBL23736191 0.85 MAPT (0.63) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL8313104 0.85 MEN1 (0.47) MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL2314047 0.84 HPGDS (0.63) GAANPC1RAB9AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111922553-A Copper surface protective agent for advanced wafer packaging field and preparation method thereof 深圳市创智成功科技有限公司 2020-11-13 — — CN claimed
CN-107971655-B High-heat-resistance organic solder flux and application thereof 永星化工(上海)有限公司 2019-12-27 — — CN claimed
US-12403128-B2 Compositions and methods for blocking sodium channels Univerity of Virginia Patent Foundation (US) 2025-09-02 — — US disclosed
CN-117655583-B High-temperature-resistant organic solder resist, organic solder mask layer of PCB and preparation process of organic solder mask layer 梅州鼎泰电路板有限公司 2024-04-05 — — CN disclosed
CN-117655583-A High-temperature-resistant organic solder resist, organic solder mask layer of PCB and preparation process of organic solder mask layer 梅州鼎泰电路板有限公司 2024-03-08 — — CN disclosed
EP-3573957-B1 COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS RIVARA MIRKO (IT) 2023-04-26 — — EP disclosed
EP-3573957-B1 COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS RIVARA MIRKO (IT) 2023-04-26 — — EP disclosed
US-20220047554-A1 COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS UNIVERSITY OF VIRGINIA 2022-02-17 — — US disclosed
US-11090289-B2 Compositions and methods for blocking sodium channels UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2021-08-17 — — US disclosed
US-11090289-B2 Compositions and methods for blocking sodium channels UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2021-08-17 — — US disclosed
CN-111922553-A Copper surface protective agent for advanced wafer packaging field and preparation method thereof 深圳市创智成功科技有限公司 2020-11-13 — — CN disclosed
WO-2018140504-A1 COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS PATEL MANOJ K (US) 2018-08-02 — — WO disclosed
WO-2018140504-A1 COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS PATEL MANOJ K (US) 2018-08-02 — — WO disclosed
CN-107971655-A A kind of high heat-resistance organic solder ability preservative and its application 永星化工(上海)有限公司 2018-05-01 — — CN disclosed
CN-102236259-A Radiation sensitivity resin composition for display element, interlayer insulation film, protective film and spacer and forming method thereof JSR CORP 2011-11-09 — — CN disclosed
US-4164480-A POLYMER STABILIZERS EASTMAN KODAK COMPANY (US) 1979-08-14 — — US disclosed
US-4105631-A MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-08-08 — — US disclosed
US-4043973-A PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS EASTMAN KODAK COMPANY (US) 1977-08-23 — — US disclosed
US-3939115-A OXADIAZOLES EASTMAN KODAK COMPANY (US) 1976-02-17 — — US disclosed
US-3936419-A Multichromophoric ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12403128-B2 Compositions and methods for blocking sodium channels SCN3A, SCN1B, SCN2B MAPK13 2204/4885MAPK12 2707/4885MAPK11 1785/4885
US-11090289-B2 Compositions and methods for blocking sodium channels SCN3A, SCN1B, SCN2B MAPK13 2204/4885MAPK12 2707/4885MAPK11 1785/4885
US-20220047554-A1 COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS SCN3A, SCN1B, SCN2B MAPK13 2204/4885MAPK12 2707/4885MAPK11 1785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.