SCHEMBL2218974

SCHEMBL2218974

CC(C)(C)OC(=O)C(N)CCCC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 3/20 0.43
LTA4H P09960 1/20 0.41
BHMT Q93088 4/20 0.41
ALDH1A1 P00352 1/20 0.40
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
GABRA2 P47869 2/20 0.39
GABRB2 P47870 2/20 0.39
GABRA4 P48169 2/20 0.39
GABRE P78334 2/20 0.39
GABRA6 Q16445 2/20 0.39
GABRG1 Q8N1C3 2/20 0.39
GABRG3 Q99928 2/20 0.39
GABRQ Q9UN88 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30439764 1.00 ENPEP (0.43) ENPEPLTA4HBHMTALDH1A1GABRP
SCHEMBL337707 0.89 CYP1A2 (0.52) ENPEPLTA4HGABRPGABRDGABRA1
SCHEMBL561334 0.89 CYP1A2 (0.52) ENPEPLTA4HGABRPGABRDGABRA1
SCHEMBL6740146 0.89 CYP1A2 (0.52) ENPEPLTA4HGABRPGABRDGABRA1
SCHEMBL28096244 0.87 CYP1A2 (0.50) ENPEPLTA4HGABRPGABRDGABRA1
Hydrochloric Acid SCHEMBL3580142 0.87 CYP1A2 (0.50) ENPEPLTA4HGABRPGABRDGABRA1
Hydrochloric Acid SCHEMBL2124734 0.87 CYP1A2 (0.50) ENPEPLTA4HGABRPGABRDGABRA1
Hydrochloric Acid SCHEMBL2124740 0.87 CYP1A2 (0.50) ENPEPLTA4HGABRPGABRDGABRA1
SCHEMBL23416460 0.86 LTA4H (0.39) LTA4HCYP1A2SLC1A1MEN1KMT2A
SCHEMBL3176136 0.86 LTA4H (0.39) LTA4HCYP1A2SLC1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637473-B2 MDM2 protein degraders REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-05-26 US disclosed
CN-121574171-A Difunctional protein degradation agent of direct targeting proteasome, preparation method and application thereof 浙大城市学院 2026-02-27 CN disclosed
CN-120040321-A Neuraminidase inhibitor based on hydrophobic tag technology and preparation method, derivative, pharmaceutical composition and application thereof 南方科技大学 2025-05-27 CN disclosed
CN-116178293-B Myelin specific magnetic resonance contrast agent, preparation method and application thereof 滨州医学院附属医院 2025-05-09 CN disclosed
CN-114716387-B High affinity agents for prostate specific membrane antigen targeting for intracavity radiation therapy of prostate cancer 约翰霍普金斯大学 2025-04-01 CN disclosed
US-20250032635-A1 LIGAND-POLAR DRUG CONJUGATES TRIPARTITE THERAPEUTICS INC. (TW) 2025-01-30 US disclosed
CN-114751874-B 1-Benzyl-4-ethylpiperazine derivatives as TRPV4-KCa2.3 coupling promoters and uses thereof 江南大学 2025-01-24 CN disclosed
CN-119161340-A PROTAC molecule derived based on AZD5305, and preparation method and application thereof 中国药科大学 2024-12-20 CN disclosed
CN-119080685-A Arginine methyltransferase 6 inhibitor, preparation method, pharmaceutical composition and application thereof 四川大学 2024-12-06 CN disclosed
CN-116375713-B DCLK1 protein degradation targeting chimeric and application thereof 中国人民解放军海军军医大学 2024-11-19 CN disclosed
EP-0990047-A2 METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID MOLECULES UTILIZING SIZING TECHNIQUES Rapigene, Inc. (US) 2000-04-05 EP disclosed
US-6027890-A DETECTING LIGAND BINDING BY INCUBATING TAGGED MEMBERS WITH BIOLOGICAL SAMPLE, SEPARATING BOUND FROM UNBOUND MEMBERS, CLEAVING TAG, THEN DETECTING BY NON-FLUORESCENT SPECTROSCOPY OR POTENTIOMETRY RAPIGENE, INC. (US) 2000-02-22 US disclosed
WO-1999005319-A9 METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY RAPIGENE INC (US) 1999-06-17 WO disclosed
WO-1999005319-A2 METHODS AND COMPOUNDS FOR ANALYZING NUCLEIC ACIDS BY MASS SPECTROMETRY RAPIGENE, INC. (US) 1999-02-04 WO disclosed
WO-1995023811-A1 NOVEL CARBOCYCLIC COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION BY INTERACTION WITH THE GPIIB/IIIA RECEPTOR COMPLEX THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-09-08 WO disclosed
EP-0541663-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS HAVING GLYCOPROTEIN HORMONE AGONISTIC OR ANTAGONISTIC ACTIVITY STICHTING CENTRAAL DIERGENEESKUNDIG INSTITUUT (NL) 1993-05-19 EP disclosed
WO-1992002542-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS HAVING GLYCOPROTEIN HORMONE AGONISTIC OR ANTAGONISTIC ACTIVITY STICHTING CENTRAAL DIERGENEESKUNDIG INSTITUUT (NL) 1992-02-20 WO disclosed
EP-0271041-A2 Atrial peptide derivatives ABBOTT LABORATORIES (US) 1988-06-15 EP disclosed
US-RE30731-E Enkephalin analogues Hudson, Derek (GB) 1981-09-01 US disclosed
US-4198398-A Enkephalin analogues HUDSON DEREK (GB) 1980-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637473-B2 MDM2 protein degraders MDM2, TP53, TP53BP1 ENPEP 2676/4885LTA4H 3140/4885BHMT 3097/4885
US-20250032635-A1 LIGAND-POLAR DRUG CONJUGATES CD274, SELPLG, PDCD1LG2 ENPEP 329/4885LTA4H 1399/4885BHMT 4734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.