Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12621845 | 0.89 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1PKM | |
| SCHEMBL13035869 | 0.84 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1PKM | |
| SCHEMBL12626029 | 0.81 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL12621982 | 0.81 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL12624020 | 0.79 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1 | |
| SCHEMBL12626006 | 0.79 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1 | |
| SCHEMBL12621987 | 0.79 | KMT2A (0.64) | L3MBTL1ALDH1A1MEN1PKMKMT2A | |
| SCHEMBL12621946 | 0.78 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL12621992 | 0.77 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1 | |
| SCHEMBL17530750 | 0.77 | NPC1 (0.58) | L3MBTL1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3906226-A1 | HTRA INHIBITORS AND CAGA INHIBITORS AND USE THEREOF | Psomagen, Inc. (US) | 2021-11-10 | — | — | EP | claimed |
| WO-2020142764-A1 | HTRA INHIBITORS AND CAGA INHIBITORS AND USE THEREOF | Psomagen Inc. (US) | 2020-07-09 | — | — | WO | claimed |
| EP-3906226-A1 | HTRA INHIBITORS AND CAGA INHIBITORS AND USE THEREOF | Psomagen, Inc. (US) | 2021-11-10 | — | — | EP | disclosed |
| WO-2020142764-A1 | HTRA INHIBITORS AND CAGA INHIBITORS AND USE THEREOF | Psomagen Inc. (US) | 2020-07-09 | — | — | WO | disclosed |